- From One Genome, Many Types of Cells. But How?
New York Times, February 23, 2009
Provides a nice introduction to how cell fate and determination are influenced by chromatin and epigenetics. Includes excellent graphics to help explain key concepts.
- Studies find elusive key to cell fate in embryo
New York Times, April 25, 2006
Easy to read article which highlights the importance of chromatin and histone modifications to cell development and differentiation.
- Nature special podcast on stem cells
June 29, 2006
Includes brief discussion of role of chromatin modifications and gene regulation to the pluripotent state of stem cells at 18 min of the podcast.
- The diverse functions of histone acetyltransferase complexes
Carrozza, Utley and Workman, Trends in Genetics, 19:321-329, 2003.
Mini-review of the multiple roles of HAT coactivator complexes.
- The highly conserved and multifunctional NuA4 HAT complex
Doyon and Cote, Current Opinions in Genetics and Development, 2004.
This review focuses on the NuA4 histone acetyltransferase complex. We have an active research program on the Piccolo NuA4 catalytic subcomplex of the megadalton NuA4 complex.
- Chromatin modifier enzymes, the histone code and cancer
Santos-Rosa and Caldas, European Journal of Cancer, 41:2381-2402, 2005
Interesting review on the cancer relevance of chromatin modification enzymes.
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Department of Biochemistry & Molecular Biology, 108 Althouse Lab, University
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This page was last updated on October 1, 2018.