Ongoing Projects

Phenotype specific manipulation of heterotrimeric G protein signaling for rice trait improvement.

The goal of this project is to elucidate and manipulate G protein signaling for improved drought resistance and yield in rice.

PI: Sarah M. Assmann
Award #: NIFA-USDA 2019-67013-29234


The In Vivo Rice RNA Structurome in Abiotic Stress Sensing and Response.

The goals of this project are to determine how RNA structure genome-wide is regulated by abiotic stressors, and conversely, how RNA structural changes contribute to abiotic stress tolerance in rice.

PI: Philip C. Bevilacqua, Co-PIs: Sarah M. Assmann, David Mathews (U. Rochester)
Award Number: NSF-IOS (Plant Genome) 13-39282:


Regulation of Heterotrimeric G Protein Signaling by Subunit Phosphorylation

The goal of this project is to use the model plant, Arabidopsis, to elucidate mechanisms of phosphorylation-based regulation of heterotrimeric G protein signaling that are broadly conserved across eukaryotes.

PI: Sarah M. Assmann
Award Number: NIH-R01GM126079


Systems biology of heterotrimeric G protein signaling in overlapping stomatal closure pathways

Goals include establishing the degree of competition vs. partitioning among the Gα units, connecting each to the ABA and CO2 signaling pathways, and developing and applying convergent network analysis onto G-Proteins.

PI: Sarah M. Assmann, Co-PI: Réka Albert
Award #: NSF-MCB 1715826:


Metabolomics of Stomatal Immunity in the Disease Triangle

The goal of this project is to identify components of the guard cell metabolome that play crucial regulatory roles in pathogen-triggered stomatal movements, and to elucidate the roles of these metabolites in the disease triangle (plant-pathogen-environment).
PI: Sixue Chen; co-PI, Sarah M. Assmann
Sponsored by the National Science Foundation


Discovery and Characterization of Novel RNA Switch Chemistry and Biology via RNA Structure-seq.

The goal of this project is to apply our Structure-seq method of RNA structure determination to elucidate new riboswitch-like mechanisms of metabolite and protein control of RNA structure in bacteria.

PI: Paul Babitzke, Co-PIs: Philip C. Bevilacqua, Sarah M. Assmann
Award from the Charles E. Kaufman Foundation