Regulation of Heterotrimeric G-Protein Signaling by Subunit Phosphorylation

PI: Sarah M. Assmann
The goal of this project is to use the model plant, Arabidopsis, to elucidate mechanisms of phosphorylation-based regulation of heterotrimeric G-protein signaling that are broadly conserved across eukaryotes.


NSF-IOS (Plant Genome) 13-39282:

The In Vivo Rice RNA Structurome in Abiotic Stress Sensing and Response.

PI: Philip C. Bevilacqua
co-PIs: Sarah M. Assmann, David Mathews (U. Rochester) 6/1/14 to 5/31/18.
The goals of this project are to determine how RNA structure genome-wide is regulated by abiotic stressors, and conversely, how RNA structural changes contribute to abiotic stress tolerance in rice.


NSF-MCB 1715826:

Systems biology of heterotrimeric G-protein signaling in overlapping stomatal closure pathways

PIs: PI Sarah M. Assmann, co-PI Réka Albert
Total Award Period: 07/01/2017 - 06/30/2021
Goals include establishing the degree of competition vs. partitioning among the Gα units, connecting each to the ABA and CO2 signaling pathways, and developing and applying convergent network analysis onto G-Proteins.


Charles E. Kaufman Foundation:

Discovery and Characterization of Novel RNA Switch Chemistry and Biology via RNA Structure-seq.

PI: Paul Babitzke
co-PI: Philip C. Bevilacqua and Sarah M. Assmann.
The goal of this project is to apply our Structure-seq method of RNA structure determination to elucidate new riboswitch- like mechanisms of metabolite and protein control of RNA structure in bacteria.


USDA-AFRI - 2014-67013- 21599

Manipulating Heterotrimeric G-protein Signaling for Improved Agronomic Traits and Drought Resistance in Rice.

PI: Sarah M. Assmann; co-PI: Hong Ma.
The goal of this project is to elucidate the mechanisms by which G-protein signaling confers improved drought resistance and yield in rice.