Lisa D. Finkelstein

 

Senior Research Fellow at National Human Genome Research Institute/National Institutes of Health

 

NHGRI/NIH

49/4A35

Bethesda, MD 20892

301-435-1907

 

lfinkels@mail.nih.gov

 

Education/Research Experience

 

2001-present

Senior Research Fellow; National  Institutes of Health, Bethesda, MD
 

1998-2001

Postdoctoral Fellow; Pennsylvania State University, University Park, PA
 

1998

Instructor/Postdoc; Oregon State University, Covallis, OR

 

1992-1997

Ph.D. Microbiology and Immunology; University of Michigan, Ann Arbor, MI
 

1988-1992

 B.S. Biology; Duke University, Durham, NC

 

 

Teaching Experience 

1998

Laboratory Instructor (Immunology); Oregon State University 

 

 

Honors

2001-2003 American Cancer Society Post-doctoral Fellowship
 
1992-1993 Human Genetics Training Grant

 

 

Publications

 

Labno CM, Lewis CM, You D, Leung DW, Takesono A, Kamberos N, Seth A, Finkelstein LD, Rosen MK, Schwartzberg PL, and Burkhardt JK.  Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.  Current Biology 13:1619-1624, 2003.

Teal HE, Xu J, Finkelstein LD, Cheng A, Paulson RF, and Correll PH.  Grb2 haploinsufficiency regulates the progression of Friend virus-induced erythroleukemia in vitro and in vivo.  Manuscript in preparation.

Finkelstein LD, Ney PA, Liu QP, Paulson RF, Correll PH.  Sf-Stk kinase activity and the Grb2 binding site are required for Epo-independent growth of primary erythroblasts infected with Friend virus.  Oncogene 21:3562-3570, 2002.

 

Takesono, A, Finkelstein, LD, and Schwartzberg, PL.  Beyond calcium: new signaling pathways for Tec family kinases.  J Cell Sci 115:3039-3048, 2002.

Finkelstein, LD and Shimizu, Y.  Role of phosphoinositide 3-kinase and the Cbl adaptor protein in coupling the a4b1 integrin to mitogen-activated protein kinase signalling.  Biochem J 345:385-392, 2000.

Finkelstein LD, Reynolds PJ, Hunt SW 3rd, Shimizu Y. Structural requirements for b1 integrin-mediated tyrosine phosphorylation in human T cells.  J Immunol 159:5355-5363, 1997.

Zell T, Hunt SW 3rd, Mobley JL, Finkelstein LD, Shimizu Y. CD28-mediated up-regulation of b1-integrin adhesion involves phosphatidylinositol 3-kinase.  J Immunol 156:883-886, 1996.

Shimizu Y, Mobley JL, Finkelstein LD, Chan AS.   A role for phosphatidylinositol 3-kinase in the regulation of b1 integrin activity by the CD2 antigen.  J Cell Biol 131:1867-1880, 1995.

 

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