ANSC 442: QUANTITATIVE GENETICS

Instructor: G. F. Barbato

Office: 201 Henning Bldg.

Email: PLEASE USE ANGEL EMAIL FOR CLASS BUSINESS

ONLINE SYLLABUS: http://www.personal.psu.edu/gfb1/442notes/

also, available via ANGEL: https://www.cms.psu.edu

2008 Lecture Schedule:

1. Administrivia

   1. ANSC 442: Quantitative Genetics

   2. Course Information

   3. Course Projects

   4. How to submit homework assignments

2. Introduction (Jan 15 - 17)

   1. Deal or No Deal

   2. Domestication and Animal Welfare

   3. A Brief History of Quantitative Genetics

3. Genetics of a Population (Jan 22 - Jan 29)

   1. Phenotypic, genotypic and gene frequencies

   2. Hardy-Weingberg (the easy way)

   3. Changing gene frequencies

4. Genetics of Small Populations (Jan 31 – Feb 7)

   1. Basic generations

   2. Continuous variation

   3. Means

5. Variances (Feb 19 - 21)

   1. Environmental variance

   2. Estimating genetic components

6. Heritability (Feb 26)

7. Selection (Feb 28 -March 4)

   1. Selection responses

   2. Experimental results

   3. Information from relatives

8. Correlated Responses (March 6 – March 11)

9. Inbreeding and Crossbreeding (Mar 13 - Mar 27)

   1. Changes in mean value

   2. Diallel crosses (Linear model)

   3. Combining Ability

10. Problems of scale (April 1- April 3)

    1. What is "scale"?

    2. Threshold characters

11. Genes and Markers and Maps (oh my!) (April 8 - April 17)

    1. What is a Genome?

    2. Major genes and genetic markers

    3. QTL analysis

    4. Mapping

12. Student Presentations (April 22 – May 1)

13. Video 2005: Evolution