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Lung Surfactants

q       Mehta, R. V.; Nagarajan, R. A Surface Chemical and Molecular Interpretation of Lung Surfactant Hysteresis. Journal of Colloid and Interface Science 89, 542-546 (1982).
 

 

 

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Lung Surfactant Monolayer Dynamics

 


Surface pressure – surface area hysteresis curve (dotted line) generated based on the kinetic model proposed.  Shown for qualitative comparison are the hysteresis loops of the first and second cycles of an in-vitro experiment (marked 1 and 2) using dipalmitoyl lecithin.  The kinetic model incorporates rate expressions associated with the compression and expansion of the monolayer, monolayer collapse, and the reentry of surfactant molecules from the aqueous subphase to the monolayer.