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Lung Surfactants q Mehta, R. V.; Nagarajan, R. A Surface Chemical and Molecular
Interpretation of Lung Surfactant Hysteresis. Journal
of Colloid and Interface Science 89, 542-546 (1982). |
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Lung Surfactant Monolayer Dynamics |
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Surface pressure – surface area
hysteresis curve (dotted line) generated based on the kinetic model
proposed. Shown for qualitative
comparison are the hysteresis loops of the first and second cycles of an in-vitro
experiment (marked 1 and 2) using dipalmitoyl lecithin. The kinetic model incorporates rate
expressions associated with the compression and expansion of the monolayer,
monolayer collapse, and the reentry of surfactant molecules from the aqueous
subphase to the monolayer. |