Study Guide and Study Questions: Mitosis and the
Reading assignments are from 'Biology', Seventh Edition
by Campbell and Reece.
Review the structure of nucleic acids on p. 87-88. Also refer
to Dr. Hamilton's handout on Organic Molecules.
Read Chapter 12. Know all bold-face terms. You do not need to
know the details of the section "The Cell Cycle Control System"(p.
Give a very brief description of the double helix structure of DNA (use Fig.
5.27on p. 88 and Fig. 16.7a on p. 297).
It is not necessary to give the structure of
the sugar-phosphate backbone. Why are the 2 polynucleotide strands
which make up a DNA molecule called 'complementary'?
Before cell division these 2 strands separate and each directs the formation
of a new complementary strand. How does this occur and why is each
original strand called a 'template'?
what a checkpoint is.
that fluctuating activities and quantities of regulatory molecules (proteins)
are the master controls of the cell cycle.
that both internal (inside the cell) and external signals also affect the
Are human somatic cells haploid or diploid? How many chromosomes
are in each of these cells? Answer these questions for human gametes
also. What is an organism's genome?
What is chromatin? What is the difference between chromatin and chromosomes?
A non-replicated chromosome is made up of 2 polynucleotide
strands. How many 'strands' are in a replicated chromosome?
How many 'strands' are in one sister chromatid?
Interphase and the mitotic phase are 2 parts of the cell cycle. What
are the subphases of interphase and briefly describe what occurs in each
The mitotic phase of the cell cycle is a 'continuum of change'. What does
this mean and why do we need to divide mitosis into phases? What
are the phases of mitosis?
What is the mitotic spindle made up of and where and when does it begin
What are the functions of the mitotic spindle?
What is a centromere? What is a kinetochore? How many kinetochores are
present in a replicated chromosome?
What is the metaphase plate (is it a physical structure?)? Explain the mechanism by which the kinetochores
help align the chromosomes along the metaphase plate.
Briefly describe cytokinesis in an animal cell and in a plant cell.
Are most of the cells in the human body actively dividing? What is
the phase name of this non-dividing state?
Help! I'm confused! Please recap the differences between:
a replicated chromosome
a non-replicated chromosome
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