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Humbert R, Adler DA, Diesteche CM, Hassett C, Omiecinski CJ, Furlong CE. The molecular basis of the human serum paraoxonase activity polymorphism. Nature Genetics 3: 73-76, 1993.

Hassett C, Sidhu JS, Aicher L, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression of amino acid variants in vitro. Human Molecular Genetics 3: 421-428, 1994.

Sidhu JS, Omiecinski CJ. Protein synthesis inhibitors exhibit a non-specific effect on phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocytes. J Biological Chemistry 273: 4769-4775, 1998.

Raaka S, Hassett C, Omiecinski CJ. Human microsomal epoxide hydrolase: 5'-flanking region genetic polymorphisms. Carcinogenesis 19: 387-393, 1998.

Ramsden R, Beck NA, Sommer KM, and Omiecinski, CJ. Phenobarbital responsiveness conferred by the rat CYP2B2 5'-flanking region in transgenic mice, Gene 228 (1-2): 169-179, 1999.

Krovat BC, Tracy JH, Omiecinski CJ. Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells. Toxicol Sci 55: 352-360, 2000.

Schilter B, Andersen MR, Acharya C, Omiecinski CJ. Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers, J Pharm Exptl Therapeut, 294, 916-922, 2000.

Beck NB, Sidhu JS, Omiecinski CJ. Baculovirus vectors repress phenobarbital-mediated gene induction and stimulate cytokine expression in primary cultures of rat hepatocytes, Gene Therapy 7: 1274-1283, 2000.

Sandberg M, Hassett C, Adman ET, Meijer J, Omiecinski CJ. Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms, J Biological Chemistry 275: 28873-28881, 2000.

Sidhu JS, Liu F, Boyle SM, Omiecinski CJ. PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes, Molecular Pharmacology 59: 1-9, 2001.

Farin FM, Janssen P, Quigley S, Abbott D, Hassett C, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT, Jr., Omiecinski CJ, Checkoway H. Genetic polymorphisms of microsomal and soluble epoxide hydrolase and the risk of Parkinson's disease, Pharmacogenetics 11: 703-708, 2001.

Auerbach SS, Ramsden R, Stoner MA, Verlinde C, Hassett C, Omiecinski CJ. Alternatively-spliced isoforms of the human constitutive androstane receptor. Nucleic Acids Research 31: 3194-3207, 2003.

Sidhu JS, Liu F, Omiecinski CJ. Phenobarbital responsiveness as a uniquely sensitive indicator of hepatocyte differentiation status: requirement of dexamethasone and extracellular matrix in establishing the functional integrity of cultured primary rat hepatocytes. Experimental Cell Research 292: 252-264, 2004.

Yamamoto M, Mise M, Matsumoto S, Ito S, Gohyama N, Ishida S, Sagara Y, Omiecinski CJ, Oguri K, Yamada H. Comparison of Genomic and cDNA Sequences of Guinea Pig CYP2B18 and Rat CYP2B2: Absence of a Phenobarbital-responsive Enhancer Module in the Upstream Region of the CYP2B18 Gene. J Biochem Molec Toxicol 18: 124-130, 2004.

Hosagrahara VP; Rettie AE, Hassett C, Omiecinski CJ. Functional analysis of human microsomal epoxide hydrolase genetic variants. Chem Biol Interac 150: 149-159, 2004.

Liang SH, Hassett C, Omiecinski CJ. Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1). Molecular Pharmacology 67: 1-11, 2005.

Abdel-Rahman SZ, Ammenheuser MM, Omiecinski CJ, Wickliffe JK, Rosenblatt JI, Ward JB Jr. Variability in human sensitivity to 1,3-butadiene: influence of polymorphisms in the 5'-flanking region of the microsomal epoxide hydrolase gene (EPHX1). Toxicological Science 85: 624-631, 2005.

Auerbach SS, Su S, Stoner MA, Omiecinski CJ. RXR-dependent transactivation by a naturally occurring structural variant of human CAR (NR1I3). Molecular Pharmacology 68, 2005, 68: 1239-1253, 2005.


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